RT Book, Section A1 Blumen, Ira J. A1 Ahn, James A2 Schafermeyer, Robert A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. SR Print(0) ID 1105687864 T1 High-Altitude Illness T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 4e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-182926-7 LK accessemergencymedicine.mhmedical.com/content.aspx?aid=1105687864 RD 2024/10/06 AB High-altitude illness (HAI) often affects young and otherwise healthy individuals. It progresses from acute mountain sickness (AMS) to potentially life-threatening high-altitude pulmonary edema (HAPE) and high-altitude cerebral edema (HACE).Acetazolamide (Diamox) has been shown to be very effective for acclimatization when staging is not possible or with individuals who are at an increased risk of HAI.Definitive treatment of HACE is descent. High-flow oxygen is indicated as soon as symptoms are recognized and dexamethasone, at an initial dose of 1 to 2 mg/kg orally or intramuscularly, can produce dramatic improvement.HAPE is the leading cause of high-altitude death other than trauma.